北京大学生物医学前沿创新中心研究员， 北京未来基因诊断高精尖创新中心研究员， 北大-清华生命科学联合中心研究员，北京大学生命科学学院教授，北京大学基因组编辑研究中心主任。魏文胜是北京大学生物化学学士、密西根州立大学遗传学博士、斯坦福大学医学院博士后。课题组专注于基因编辑、新型基因与细胞治疗以及 高通量功能基因组学技术的发展，重点研究癌症和感染等重大疾病的分子机制，以提供高效治疗方法的新药物靶点和思路。

代表性论文

1. Bao Y, Pan Q, Xu P, Liu Z, Zhang Z, Liu Y, Xu Y, Yu Y, Zhou Z*, Wei W*. (2023) Unbiased Interrogation of Functional Lysine Residues in Human Proteome. Molecular Cell 83, 4614-4632 e4616.
2. Yi Z, Zhang X, Tang W, Yu Y, Wei X, Zhang X, and Wei W*. (2023) Strand-Selective Base Editing in Mitochondrial DNA using Programmable Deaminases with Targeted Nickase. Nat Biotechnol 42, 498-509.
3. Qu L, Yi Z, Shen Y, Lin L, Chen F, Xu Y, Wu Z, Tang H, Zhang X, Tian F, Wang C, Xiao X, Dong X, Guo L, Lu S, Yang C, Tang C, Yang Y, Yu W, Wang, J, Zhou Y, Huang Q, Yisimayi A, Liu S, Huang WJ, Cao Y, Wang Y, Zhou Z, Peng X, Wang J, Xie X, Wei W*. (2022) Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants. Cell 185, 1728-1744 e1716.
4. Yi Z, Qu L, Tang H, Liu Z, Liu Y, Tian F, Wang C, Zhang X, Feng Z, Yu Y, Yuan P, Yi Z, Zhao Y, Wei W*. (2022) Engineered circular ADAR-recruiting RNAs increase the efficiency and fidelity of RNA editing in vitro and in vivo. Nature Biotechnology 40(6): 946-955.
5. Xu P, Liu Z, Liu Y, Ma H, Xu Y, Bao Y, Zhu S, Cao Z, Wu Z, Zhou Z and Wei W*. (2021) Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAs. Nature Biotechnology 39(11), 1403–1413.
6. Qu L, Yi Z, Zhu S, Wang C, Cao Z, Zhou Z, Yuan P, Tian F, Liu Z, Bao Y, Zhao Y, Wei W*. (2019) Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs. Nature Biotechnology 37, 1059-1069.
7. Zhao X, Zhang G, Liu S, Chen X, Peng R, Dai L, Qu X, Li S, Song H, Gao Z, Yuan P, Liu Z, Li C, Shang Z, Li Y, Zhang M, Qi J, Wang H, Du N, Wu Y, Bi YH, Gao S, Shi Y, Yan J, Zhang Y, Xie Z*, Wei W* and Gao GF*. (2019) Human neonatal Fc receptor is the cellular uncoating receptor for enterovirus B. Cell 177, 1-13.
8. Liu Y, Cao Z, Wang Y, Guo Y, Xu P, Yuan P, Liu Z, He Y and Wei W*. (2018) Genome-wide screening for functional long noncoding RNAs in human cells by Cas9 targeting of splice sites. Nature Biotechnology 36, 1203-1210.
9. Zhu S, Li W, Liu J, Chen C-H, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu X* & Wei W*. (2016) Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR library. Nature Biotechnology 34, 1279-1286.
10. Zhou Y, Zhu S, Cai C, Yuan P, Li C, Huang Y and Wei W*. (2014) High-throughput Screening of a CRISPR/Cas Library for Functional Genomics in Human Cells. Nature 509, 487-91.