Publications -Beijing Advanced Innovation Center for Genomics

Nature Cancer \| Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms
Cancer Cell \| Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer
Cell \| Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes
National Science Review \| Pan-cancer integrative analyses dissect the remodeling of endothelial cells in human cancers
Cancer Discovery \| Single-cell chromatin accessibility analysis reveals the epigenetic basis and signature transcription factors for the molecular subtypes of colorectal cancers
Nature \| Fan Bai's Team reveals the whole-genome variations and evolutionary characteristics of liver cancer in the Chinese population
Mol Cell｜ The Wensheng Wei team has achieved the functional decoding of lysine residues in the human proteome
Cell Research \| scNanoCOOL-seq: a long-read single-cell sequencing method for multi-omics profiling within individual cells
NAR \| High-Precision Haplotype Phasing Using Single-Sperm Long-Read Genome Sequencing
Cell \| A Pan-Cancer Single Cell Panorama of Human Natural Killer Cells
Protein & Cell \| Drug repurposing screening and mechanism analysis based on human colorectal cancer organoids
Science \| Single-Cell Multi-Omics Technology Revealing the Relationship Between the 3D Genome Architecture and Gene Expression During Development
National Science Review∣Integrative single-cell multiomics analyses dissect molecular signatures of intratumoral heterogeneities and differentiation states of human gastric cancer
Nature Biotechnology \| CRISPR-free, strand-selective mitochondrial DNA base editing by introducing nickase
Cell \| Zemin Zhang Lab was invited to review the milestones of cancer genomics and discuss new frontiers in the future
PNAS \| Sensitive bacterial Vm sensors revealed the excitability of bacterial Vm and its role in antibiotic tolerance
Genome Biology \| Parallel single-cell and bulk transcriptome analyses reveal key features of the gastric tumor microenvironment
Cell Research \| scNanoATAC-seq: a long-read single-cell ATAC sequencing method to detect chromatin accessibility and genetic variants simultaneously within an individual cell
Cell Discovery \| Single-cell profiling reveals molecular basis of malignant phenotypes and tumor microenvironments in small bowel adenocarcinomas
Genome Medicine \| Single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer tumors