Rm. 201, Integrated Science Research Center No.2,Peking University
Wulan Deng obtained B.S. in Biological Science from Peking University in 2016, and Ph.D. in Molecular and Cell Biology from University of Pennyslvania in 2012, during which she was awarded multiple honors including President Gutmann Leadership Award, Distiguished Research Trainee Award, and ASH Merit Award from American Society of Hematology. After graduation, she joined the Transcription Imaging Consortium (TIC) at the Janelia Research Campus of HHMI as a Research Specialist with mentorship from former HHMI president Dr. Robert Tjian and Dr. Robert Singer. She was a Helen Hey Whitney Postdoctoral fellow. In 2017, she followed Dr. Robert Tjian and moved to University of California, Berkeley as a postdoctoral researcher. She joined BIOPIC and School of Life Sciences in Peking University this August. Her research group is focused on the regulation mechanisms of transcription and chromatin, and their dynamics at single molecular level.
1. Z. Wang, and W. Deng#, Dynamic transcription regulation at the single-molecule level. Developmental Biology 482, 67–81(2022).
2. W. Deng#, X. Shi, R. Tjian, T. E. E. Lionnet, and R. H. Singer#, CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells. Proceedings of the National Academy of Sciences 112, 11870-11875 (2015).
3. S. C. Knight, L. Xie, W. Deng, B. Guglielmi, L. B. Witkowsky, L. Bosanac, E. T. Zhang, M. E. Beheiry, J.-B. Masson, M. Dahan, and Z. Liu, Dynamics of CRISPR-Cas9 genome interrogation in living cells. Science 350, 823-827 (2015).
4. W. Deng*, J. W. Rupon*, I. Krivega, L. Breda, I. Motta, K. S. Jahn, A. Reik, P. D. Gregory, S. Rivella, A. Dean, and G. A. Blobel, Reactivation of developmentally silenced globin genes by forced chromatin looping, Cell 158, 849-860 (2014).
5. W. Deng, J. Lee, H. Wang, J. Miller, A. Reik, P. D. Gregory, A. Dean, and G. A. Blobel, Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell 149, 1233-1244 (2012).
6. T. Tripic*, W. Deng*, Y. Cheng, Y. Zhang, C. R. Vakoc, G. D. Gregory, R. C. Hardison, G. A. Blobel, SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood 113, 2191–2201 (2009).